Research 2011—

更新日2017.04.07

研究内容

 

PM2.5、飛来黄砂、可塑剤、洗剤など、身の回りの化学物質が、免疫系、生殖系に及ぼす影響について調べています

 

 

論文一覧(2011~)

 

He M, Ichinose T, Yoshida S, Shiba F, Arashidani K, Takano H, Sun G, Shibamoto T. Differences in allergic inflammatory responses in murine lungs: comparison of PM2.5 and coarse PM collected during the hazy events in a Chinese city. Inhal Toxicol. 2016

Yoshida S, Ichinose T, Arashidani K, He M, Takano H, Shibamoto T. Effects of Fetal Exposure to Asian Sand Dust on Development and Reproduction in Male Offspring. Int J Environ Res Public Health. 2016

Sadakane K, Ichinose T, Nishikawa M, Takano H, Shibamoto T. Co-exposure to zymosan A and heat-inactivated Asian sand dust exacerbates ovalbumin-induced murine lung eosinophilia. Allergy Asthma Clin Immunol. 2016

Honda A, Sawahara T, Hayashi T, Tsuji K, Fukushima W, Oishi M, Kitamura G, Kudo H, Ito S, Yoshida S, Ichinose T, Ueda K, Takano H. Biological factor related to Asian sand dust particles contributes to the exacerbation of asthma. J Appl Toxicol. 2017

Bekki K, Ito T, Yoshida Y, He C, Arashidani K, He M, Sun G, Zeng Y, Sone H, Kunugita N, Ichinose T. PM2.5 collected in China causes inflammatory and oxidative stress responses in macrophages through the multiple pathways. Environ Toxicol Pharmacol. 2016

He M, Ichinose T, Yoshida S, Takano H, Nishikawa M, Shibamoto T, Sun G. Exposure to bisphenol A enhanced lung eosinophilia in adult male mice. Allergy Asthma Clin Immunol. 2016

Yanagisawa R, Koike E, Win-Shwe TT, Ichinose T, Takano H. Low-dose benzo[a]pyrene aggravates allergic airway inflammation in mice. J Appl Toxicol. 2016

He M, Ichinose T, Kobayashi M, Arashidani K, Yoshida S, Nishikawa M, Takano H, Sun G, Shibamoto T. Differences in allergic inflammatory responses between urban PM2.5 and fine particle derived from desert-dust in murine lungs. Toxicol Appl Pharmacol. 2016

He M, Ichinose T, Song Y, Yoshida Y, Bekki K, Arashidani K, Yoshida S, Nishikawa M, Takano H, Shibamoto T, Sun G.. Desert dust induces TLR signaling to trigger Th2-dominant lung allergic inflammation via a MyD88-dependent signaling pathway. Toxicol Appl Pharmacol. 2016

He M, Ichinose T, Song Y, Yoshida Y, Kobayashi F, Maki T, Yoshida S, Takano H, Shibamoto T, Sun G: The Role of Toll-Like Receptors and Myeloid Differentiation Factor 88 in Bjerkandera adusta-Induced Lung Inflammation. Int Arch Allergy Immunol. 2015

He M, Ichinose T, Ren Y, Song Y, Yoshida Y, Arashidani K, Yoshida S, Nishikawa M, Takano H, Sun G: PM2.5-rich dust collected from the air in Fukuoka, Kyushu, Japan, can exacerbate murine lung eosinophilia. Inhal Toxicol. 2015

Takeshita S, Tokunaga T, Tanabe Y, Arinami T, Ichinose T, Noguchi E: Asian sand dust aggregate causes atopic dermatitis-like symptoms in Nc/Nga mice. Allergy Asthma Clin Immunol. 2015

Sadakane K, Ichinose T: Effect of the hand antiseptic agents benzalkonium chloride, povidone-iodine, ethanol, and chlorhexidine gluconate on atopic dermatitis in NC/Nga mice. Int J Med Sci. 2015

Michikawa T, Ueda K, Takeuchi A, Kinoshita M, Hayashi H, Ichinose T, Nitta H: Impact of short-term exposure to fine particulate matter on emergency ambulance dispatches in Japan. J Epidemiol Community Health. 2015

Ren Y, Ichinose T, He M, Arashidani K, Yoshida Y, Yoshida S, Nishikawa M, Takano H, Sun G, Shibamoto T: Aggravation of ovalbumin-induced murine asthma by co-exposure to desert-dust and organic chemicals: an animal model study. Environ Health. 2014

Sadakane K, Ichinose T, Takano H, Yanagisawa R, Koike E, Inoue KI: The alkylphenols 4-nonylphenol, 4-tert-octylphenol and 4-tert-butylphenol aggravate atopic dermatitis-like skin lesions in NC/Nga mice. J Appl Toxicol. 2014

Ichinose T: [Progress of the research on air pollution (PM2.5, Asian sand dust, etc) and allergy]. Arerugi. 2014

Mimura T, Ichinose T, Yamagami S, Fujishima H, Kamei Y, Goto M, Takada S, Matsubara M: Airborne particulate matter (PM2.5) and the prevalence of allergic conjunctivitis in Japan. Sci Total Environ. 2014

Yanagisawa R, Koike E, Ichinose T, Takano H: Obese mice are resistant to eosinophilic airway inflammation induced by diesel exhaust particles. J Appl Toxicol. 2013

Honda A, Matsuda Y, Murayama R, Tsuji K, Nishikawa M, Koike E, Yoshida S, Ichinose T, Takano H: Effects of Asian sand dust particles on the respiratory and immune system. J Appl Toxicol. 2014

Liu B, Ichinose T, He M, Kobayashi F, Maki T, Yoshida S, Yoshida Y, Arashidani K, Takano H, Nishikawa M, Sun G, Shibamoto T: Lung inflammation by fungus, Bjerkandera adusta isolated from Asian sand dust (ASD) aerosol and enhancement of ovalbumin-induced lung eosinophilia by ASD and the fungus in mice. Allergy Asthma Clin Immunol. 2014

Sadakane K, Ichinose T, Takano H, Yanagisawa R, Koike E: Effects of oral administration of di-(2-ethylhexyl) and diisononyl phthalates on atopic dermatitis in NC/Nga mice. Immunopharmacol Immunotoxicol. 2014

Ren Y, Ichinose T, He M, Song Y, Yoshida Y, Yoshida S, Nishikawa M, Takano H, Sun G, Shibamoto T: Enhancement of OVA-induced murine lung eosinophilia by co-exposure to contamination levels of LPS in Asian sand dust and heated dust. Allergy Asthma Clin Immunol. 2014

Song Y, Ichinose T, Morita K, Nakanishi T, Kanazawa T, Yoshida Y: Asian sand dust causes subacute peripheral immune modification with NF-κB activation. Environ Toxicol. 2013

He M, Ichinose T, Song Y, Yoshida Y, Arashidani K, Yoshida S, Liu B, Nishikawa M, Takano H, Sun G: Effects of two Asian sand dusts transported from the dust source regions of Inner Mongolia and northeast China on murine lung eosinophilia. Toxicol Appl Pharmacol. 2013

Tanaka M, Takano H, Fujitani Y, Hirano S, Ichinose T, Shimada A, Inoue KI: Effects of exposure to nanoparticle-rich diesel exhaust on 8-OHdG synthesis in the mouse asthmatic lung. Exp Ther Med. 2013

He M, Inoue K, Yoshida S, Tanaka M, Takano H, Sun G, Ichinose T: Effects of airway exposure to di-(2-ethylhexyl) phthalate on allergic rhinitis. Immunopharmacol Immunotoxicol. 2013

Tanaka M, Aoki Y, Takano H, Fujitani Y, Hirano S, Nakamura R, Sone Y, Kiyono M, Ichinose T, Itoh T, Inoue K: Effects of exposure to nanoparticle-rich or -depleted diesel exhaust on allergic pathophysiology in the murine lung. J Toxicol Sci. 2013

He M, Ichinose T, Yoshida S, Takano H, Nishikawa M, Sun G, Shibamoto T: Induction of immune tolerance and reduction of aggravated lung eosinophilia by co-exposure to Asian sand dust and ovalbumin for 14 weeks in mice. Allergy Asthma Clin Immunol. 2013

Sadakane K, Ichinose T, Takano H, Yanagisawa R, Inoue K, Kawazato H, Yasuda A, Hayakawa K: Organic chemicals in diesel exhaust particles enhance picryl chloride-induced atopic dermatitis in NC/Nga mice. Int Arch Allergy Immunol. 2013

Yanagisawa R, Warabi E, Inoue K, Yanagawa T, Koike E, Ichinose T, Takano H, Ishii T: Peroxiredoxin I null mice exhibits reduced acute lung inflammation following ozone exposure. J Biochem. 2012

He M, Ichinose T, Yoshida S, Takano H, Nishikawa M, Mori I, Sun G, Shibamoto T: Aggravating effects of Asian sand dust on lung eosinophilia in mice immunized beforehand by ovalbumin. Inhal Toxicol. 2012

Yoshida S, Takano H, Nishikawa M, Miao H, Ichinose T: Effects of fetal exposure to urban particulate matter on the immune system of male mouse offspring. Biol Pharm Bull. 2012

Yasuda A, Inoue K, Sanbongi C, Yanagisawa R, Ichinose T, Tanaka M, Yoshikawa T, Takano H: Dietary supplementation with fructooligosaccharides attenuates allergic peritonitis in mice. Biochem Biophys Res Commun. 2012

He M, Ichinose T, Yoshida S, Yamamoto S, Inoue K, Takano H, Yanagisawa R, Nishikawa M, Mori I, Sun G, Shibamoto T: Asian sand dust enhances murine lung inflammation caused by Klebsiella pneumoniae. Toxicol Appl Pharmacol. 2012

Ding N, Kunugita N, Ichinose T, Song Y, Yokoyama M, Arashidani K, Yoshida Y: Intratracheal administration of fullerene nanoparticles activates splenic CD11b+ cells. J Hazard Mater. 2011

Inoue K, Yanagisawa R, Koike E, Nakamura R, Ichinose T, Tasaka S, Kiyono M, Takano H: Effects of carbon black nanoparticles on elastase-induced emphysematous lung injury in mice. Basic Clin Pharmacol Toxicol. 2011

 

2002〜2010年までの論文一覧はこちら